The LYMPH trial: comparing microsurgical with conservative treatment for chronic breast cancer-associated lymphoedema – study protocol of a pragmatic randomised international multicentre superiority trialElisabeth A Kappos, Yvonne Haas, Alexandra Schulz, Florian Peters, Shakuntala Savanthrapadian, Julia Stoffel, Maria C Katapodi, Rosine Mucklow, Benedict Kaiser, Alexander Haumer, Stephanie Etter, Marco Cattaneo, Daniel Staub, Karin Ribi, Jane ShawSee the full list of authors
17 February 2025
Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women undergoing surgery for breast cancerEmma Sansalone, Alison Zucca, Mitch J Duncan, Owen Morris, Stephen Ridley Smith, Sancha Robinson, Rebecca Chenery, Helen Moore, Priscilla Viana da Silva, Lara Riley, Anna Palazzi-Parsons, Penny Reeves, Christopher Oldmeadow, Rebecca Wyse
7 February 2025
Phase I trial on the safety of olprinone for low central venous pressure management aimed at haemorrhage control during open and laparoscopic hepatectomy: a study protocolYuya Miura, Teiichi Sugiura, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Yoshiyasu Kato, Takuya Oyakawa, Eiji Ando, Sunao Tamai, Katsuhiko Uesaka
7 February 2025
Pathway Of Low Anterior Resection syndrome (LARS) relief after Surgery (POLARiS): protocol for an international, open-label, multi-arm, phase 3 randomised superiority trial within a cohort, with economic evaluation, process evaluation and qualitative sub-study, to explore the natural history of LARS and compare transanal irrigation and sacral neuromodulation to optimised conservative management for people with major LARS following a high or low anterior resection for colorectal cancerJulie Croft, Emily Farrow, Alexandra Harriet Coxon-Meggy, Katie Gordon, Neil Corrigan, Hannah Mather, Deborah D Stocken, Megan Dale, Huey Yi Chong, Judith White, Laura Knight, Alun Meggy, Christina Lloydwin, Betty Tan, Ashley DouglasSee the full list of authors
3 February 2025
Using Days Alive and Out of Hospital to measure inequities and explore pathways through which inequities emerge after coronary artery bypass grafting in Aotearoa New Zealand: a secondary data analysis using a retrospective cohortLuke Boyle, Elana Curtis, Sarah-Jane Paine, Jade Tamatea, Thomas Lumley, Alan Forbes Merry
3 February 2025
Spatial and temporal changes of breast-conserving surgery rates and its influential factors among Chinese patients with breast cancer from 2013 to 2019: a registry-based studyQueran Lin, Shunrong Li, Tongrui Shang, Xiujuan Gui, Liling Zhu, Yuan Yang, Ziliang Zhong, Xiaoyu Wang, Lingyan Dai, Jianli Zhao, Yanjie Xu, Qianru Chen, Qing Yan, Xiaoliang Huang, Wei HuSee the full list of authors
2 February 2025
NIFTy: near-infrared fluorescence (NIRF) imaging to prevent postsurgical hypoparathyroidism (PoSH) after thyroid surgery—a phase II/III pragmatic, multicentre randomised controlled trial protocol in patients undergoing a total or completion thyroidectomyJulie Croft, Gemma Ainsworth, Neil Corrigan, Katie Gordon, Anna Perry, Maureen Twiddy, Mark Strachan, Jonathan Wadsley, Hisham Mehanna, Neil Sharma, Elizabeth Glenister, Deborah D Stocken, Sabapathy Prakash P Balasubramanian
30 January 2025
Understanding the impact of racism on surgical outcomes in settler nation-states USA and Canada: a protocol for a systematic review and meta-analysisIfeoluwa Adedipe, Tyara Marchand, Saffa Aziz, Mirna Matta, Mary Brindle, Oluwatomilayo Daodu
29 January 2025
Exploratory study of patients’ and carers’ preferences for postdischarge surgical wound monitoring using survey and interviewsJudith Tanner, Lyn Brierley Jones, Nigel Westwood, Melissa Rochon, Catherine Wloch, Luke J Rogers, Ricky Vaja, Jeremy Dearling, Keith Wilson, Pauline Harrington, Colin S Brown, Gavin Murphy
25 January 2025
Protocol for a multicentre, prospective, open-label, randomised controlled trial to compare PROs and safety outcomes between preoperative and postmastectomy radiotherapy in locally advanced breast cancer patients with immediate reconstruction via a deep inferior epigastric perforator flap (CAPPELLA) in ChinaShuang Hao, Jianjing Hou, Li Zhang, Changming Zhou, Yifeng Hou, Keda Yu, Zhen Hu, Guangyu Liu, Genhong Di, Zhi Min Shao, Xiaoli Yu, Jiong Wu
20 January 2025
